Skip to Content
MilliporeSigma
All Photos(3)

Documents

SAB4501465

Sigma-Aldrich

Anti-HSP10 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

CHAPERONIN 10 HOMOLOG, GroES HOMOLOG, HEAT-SHOCK 10-KD PROTEIN

Sign Into View Organizational & Contract Pricing
All Photos(3)

About This Item

MDL number:
MFCD03455104
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 10 kDa

species reactivity

rat, mouse, human

concentration

~1 mg/mL

technique(s)

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI accession no.

P61604

UniProt accession no.

P61604

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HSPE1(3336)

Related Categories

General description

Anti-HSP10 Antibody detects endogenous levels of total HSP10 protein.
HSP10 (heat shock protein family E member 1) is a molecular chaperone protein, located in mitochondria. It is encoded by HSPE1 (heat shock protein family E member 1) gene, that is located on human chromosome 2q33.1.

Immunogen

The antiserum was produced against synthesized peptide derived from human HSP10.

Immunogen Range: 51-100

Application

Anti-HSP10 antibody has been used in microarray and western blotting.

Biochem/physiol Actions

Overexpression of HSP10 (heat shock protein family E member 1) protein blocks apoptosis and results in poor prognosis of astrocytoma. It participates in immunomodulation and tumor progression.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Not finding the right product?  

Try our Product Selector Tool.

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Hsp10 nuclear localization and changes in lung cells response to cigarette smoke suggest novel roles for this chaperonin.
Corrao S, et al.
Open Biology, 4(10) (2014)
Juha J Hulmi et al.
Free radical biology & medicine, 99, 308-322 (2016-10-23)
Protein homeostasis in cells, proteostasis, is maintained through several integrated processes and pathways and its dysregulation may mediate pathology in many diseases including Duchenne muscular dystrophy (DMD). Oxidative stress, heat shock proteins, endoplasmic reticulum (ER) stress and its response, i.e.
Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.
Hulmi JJ, et al.
Free Radical Biology & Medicine, 99, 308-322 (2016)
Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins.
Karvinen S, et al.
Experimental Gerontology, 79, 46-54 (2016)
Elevated expression of HSP10 protein inhibits apoptosis and associates with poor prognosis of astrocytoma.
Fan W, et al.
PLoS ONE, 12(10) (2017)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service