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SAB5701829

Sigma-Aldrich

Anti-Phospho-p53-T55 antibody produced in rabbit

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

Quality Level

antibody product type

primary antibodies

clone

monoclonal

form

liquid

species reactivity

mouse, human, rat

concentration

2 mg/mL

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pThr55)

Gene Information

human ... TP53(7157)

General description

This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]

Immunogen

A phospho specific peptide corresponding to residues surrounding T55 of human p53

Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

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wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

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