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SML0473

Sigma-Aldrich

Noladin ether

≥98% (HPLC)

Synonym(s):

2-Arachidonylglyceryl ether, 2-[(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraen-1-yloxy]-1,3-propanediol; 2-AG ether, HU 310

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About This Item

Empirical Formula (Hill Notation):
C23H40O3
CAS Number:
222723-55-9
Molecular Weight:
364.56
EC Number:
200-578-6
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

solution

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

concentration

10 mg/mL in ethanol (1% w/v)

color

colorless to light yellow

shipped in

dry ice

storage temp.

−70°C

InChI

1S/C23H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-26-23(21-24)22-25/h6-7,9-10,12-13,15-16,23-25H,2-5,8,11,14,17-22H2,1H3/b7-6-,10-9-,13-12-,16-15-

InChI key

CUJUUWXZAQHCNC-DOFZRALJSA-N

Biochem/physiol Actions

Noladin ether (2-Arachidonyl glycerol ether) is a stable analog of the endogenous cannabanoid 2-Arachidonylglycerol (2-AG) with selectivity for CB1 receptors. Noladin ether is a CB1 agonist. The Ki values for CB1 vs CB2 receptors are 21.2 nM and 3 mM, respectively. Noladin ether induces sedation and has modest antinociceptive activity in vivo, and reduces inter ocular pressure after administration in the eye.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

hcodes

H225,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

wgk_germany

WGK 2

flash_point_f

closed cup

flash_point_c

closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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