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SML0544

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GRI977143

≥98% (HPLC)

Synonym(s):

2-[[3-(1,3-Dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]-benzoic acid

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About This Item

Empirical Formula (Hill Notation):
C22H17NO4S
CAS Number:
325850-81-5
Molecular Weight:
391.44
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to light brown

solubility

DMSO: 10 mg/mL, clear

storage temp.

2-8°C

InChI

1S/C22H17NO4S/c24-20-16-9-3-6-14-7-4-10-17(19(14)16)21(25)23(20)12-5-13-28-18-11-2-1-8-15(18)22(26)27/h1-4,6-11H,5,12-13H2,(H,26,27)

InChI key

GMVZUCHUOYUMLL-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

GRI977143 is a potent, specific LPA2 receptor agonist with no affinity for other LPA receptors. GRI977143 inhibits the initiation of apoptosis induced by adriamycin or serum withdrawal in MEFs derived from LPA2 knock-out mice transfected with an LPA2 expression vector, but has no affect in non-transfected cells.

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

hcodes

H302,H410

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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