Skip to Content
MilliporeSigma
All Photos(1)

Documents

SML2791

Sigma-Aldrich

SBI-797812

≥98% (HPLC)

Synonym(s):

1-[4-(8-Oxa-3-azabicyclo[3.2.1]octane-3-sulfonyl)-phenyl]-3-pyridin-4-ylmethylurea, N-[4-(8-Oxa-3-azabicyclo[3.2.1]oct-3-ylsulfonyl)phenyl]-N′-(4-pyridinylmethyl)-urea

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C19H22N4O4S
CAS Number:
2237268-08-3
Molecular Weight:
402.47
MDL number:
MFCD32197237
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(NC1=CC=C(S(=O)(N(C2)C[C@H]3O[C@@H]2CC3)=O)C=C1)NCC4=CC=NC=C4

Biochem/physiol Actions

SBI-797812 is a cell penetrant and potent activator of nicotinamide phosphoribosyltransferase (NAMPT) that increases intracellular levels of NMN and NAD+ in cells. SBI-797812 blocks binding of inhibitors to NAMPT and shifts the reaction equilibrium towards NMN formation. It elevates levels of NAD+ in mice liver.

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service