SML3439
IXA4
98% (HPLC)
Synonym(s):
N-Methyl-N-[2-(4-methylphenoxy)ethyl]-4-[(1-oxo-3-phenoxypropyl)amino]-1H-pyrazole-1-acetamide
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All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C24H28N4O4
CAS Number:
Molecular Weight:
436.50
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
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Quality Level
assay
98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
−20°C
SMILES string
O=C(CN1N=CC(NC(CCOC2=CC=CC=C2)=O)=C1)N(C)CCOC3=CC=C(C=C3)C
Biochem/physiol Actions
IXA4 is a nontoxic, potent and highly selective IRE1-XBP1s signaling activator that induce ER proteostasis remodeling. IXA4 reduced Aβ levels and prevents APP-associated mitochondrial dysfunction in CHO7PA2 cells expressing the V717F APP (APPV717F) mutant.
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
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