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T4071

SAFC

L-Threonine

Pharma Manufacturing

Synonym(s):

(2S,3R)-2-Amino-3-hydroxybutyric acid

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About This Item

Linear Formula:
CH3CH(OH)CH(NH2)CO2H
CAS Number:
72-19-5
Molecular Weight:
119.12
Beilstein/REAXYS Number:
1721646
EC Number:
200-774-1
MDL number:
MFCD00064270
UNSPSC Code:
12352209
NACRES:
NA.26

biological source

non-animal source

Quality Level

400

assay

≥98.5%

form

crystalline powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, heavy metals, trace metals, residual solvents, tested

mp

256 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL

suitability

suitable for manufacturing use

foreign activity

cytotoxicity, tested

SMILES string

C[C@@H](O)[C@H](N)C(O)=O

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1

InChI key

AYFVYJQAPQTCCC-GBXIJSLDSA-N

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General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.
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Application

L-Threonine is a β-hydroxy-α-amino acid. It is an essential amino acid and can be used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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