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T8250

Sigma-Aldrich

D-Threonine

≥98% (TLC)

Synonym(s):

(2R,3S)-2-Amino-3-hydroxybutyric acid, D-α-Amino-β-hydroxybutyric acid

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About This Item

Empirical Formula (Hill Notation):
C4H9NO3
CAS Number:
632-20-2
Molecular Weight:
119.12
Beilstein/REAXYS Number:
1721643
EC Number:
211-171-8
MDL number:
MFCD00064269
UNSPSC Code:
12352209
PubChem Substance ID:
24900513

Quality Level

200

assay

≥98% (TLC)

form

powder or crystals

technique(s)

UHPLC: suitable

color

white

mp

274 °C

solubility

H2O: soluble

SMILES string

C[C@H](O)[C@@H](N)C(O)=O

InChI

1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m0/s1

InChI key

AYFVYJQAPQTCCC-STHAYSLISA-N

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General description

D-Threonine is sweet and toxic in nature.It acts as an inhibitor of L-threonine dehydratase.

Application

D-Threonine has been used as a constituent of standard mix in Ultra-high performance liquid chromatography (UHPLC) system for quantification of amino acid racemization.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Kateryna Fesko et al.
Bioorganic & medicinal chemistry letters, 18(22), 5987-5990 (2008-09-02)
The Y265A mutant of alanine racemase (alrY265A) was evaluated as a catalyst for the synthesis of beta-hydroxy-alpha-amino acids. It promotes the PLP-dependent aldol condensation of glycine with a range of aromatic aldehydes. The desired products were obtained with complete stereocontrol
Alessandro Paiardini et al.
Biochimica et biophysica acta, 1647(1-2), 214-219 (2003-04-11)
Vitamin B(6)-dependent enzymes may be grouped into five evolutionarily unrelated families, each having a different fold. Within fold type I enzymes, L-threonine aldolase (L-TA) and fungal alanine racemase (AlaRac) belong to a subgroup of structurally and mechanistically closely related proteins
The Journal of Biological Chemistry, 244 (1969)
Fishmeal with different levels of biogenic amines in aquafeed: Comparison of feed protein quality, fish growth performance, and metabolism
Jasour M, et al.
Aquaculture (Amsterdam, Netherlands), 488, 80-89 (2018)
Test, 244 (1969)
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