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PHL82680

Vicine

phyproof® Reference Substance

Synonym(s):

2,6-Diamino-5-(β-D-glucopyranosyloxy)-4(1H)-pyrimidinone, Divicine 5-(β-D-glucopyranoside, NSC 95092, Vicioside

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About This Item

Empirical Formula (Hill Notation):
C10H16N4O7
CAS Number:
152-93-2
Molecular Weight:
304.26
Beilstein/REAXYS Number:
44407
MDL number:
MFCD00270447
UNSPSC Code:
41116107
NACRES:
NA.24

grade

primary reference standard

product line

phyproof® Reference Substance

assay

≥95.0% (HPLC)

form

powder

manufacturer/tradename

PhytoLab

SMILES string

O[C@@H]1[C@@H](O)[C@H](OC2=C(N)NC(N)=NC2=O)O[C@H](CO)[C@H]1O

InChI

1S/C10H16N4O7/c11-7-6(8(19)14-10(12)13-7)21-9-5(18)4(17)3(16)2(1-15)20-9/h2-5,9,15-18H,1H2,(H5,11,12,13,14,19)/t2-,3-,4+,5-,9+/m1/s1

InChI key

KGNGTSCIQCLKEH-SYCVNHKBSA-N

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General description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Application


  • Vicine in Diabetes Treatment: Vicine, a pyrimidine nucleoside analog, is researched extensively for its potential therapeutic effects in diabetes management. Studies focus on its ability to modulate blood glucose levels and improve insulin sensitivity, making it a promising compound in diabetes treatment strategies (Abasilim et al., 2023).

  • Antiviral Applications: As a nucleoside enzyme inhibitor, Vicine is under investigation for its antiviral properties. Research includes its efficacy against various viral pathogens, supporting its role in the development of new antiviral drugs (Mofidifar et al., 2024).

  • Neuroprotective Studies: Vicine is explored for its neuroprotective effects, particularly in preventing oxidative stress and neuronal damage. This research is vital for developing treatments for neurodegenerative diseases such as Alzheimer′s and Parkinson′s (Zeng et al., 2024).

  • Cardiovascular Health Research: The impact of Vicine on cardiovascular health is also a significant area of study. Research focuses on its potential to reduce heart disease risk factors, including cholesterol levels and hypertension, highlighting its cardiovascular benefits (Melanie KF et al., 2024).

  • Scientific Research and Biochemistry Applications: High-purity Vicine is crucial for laboratory use, especially in biochemical studies where it serves as a reference compound. Its role in enzyme inhibition and metabolic pathways provides essential insights into cellular processes and disease mechanisms (Ural et al., 2024).

Legal Information

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
115136127

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