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1013512

USP

Almotriptan malate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

3-[2-(Dimethylamino)ethyl]-5-(pyrrolidin-1-ylsulfonylmethyl )-1H-indole malate, PNU 180638

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About This Item

Empirical Formula (Hill Notation):
C17H25N3O2S · C4H6O5
CAS Number:
181183-52-8
Molecular Weight:
469.55
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

almotriptan

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

InChI

1S/C17H25N3O2S.C4H6O5/c1-19(2)10-7-15-12-18-17-6-5-14(11-16(15)17)13-23(21,22)20-8-3-4-9-20;5-2(4(8)9)1-3(6)7/h5-6,11-12,18H,3-4,7-10,13H2,1-2H3;2,5H,1H2,(H,6,7)(H,8,9)

InChI key

QHATUKWEVNMHRY-UHFFFAOYSA-N

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Related Categories

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Almotriptan malate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Almotriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Almotriptan has low nanomolar affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower. Affinity for 5-HT(7) and 5-HT(1A) receptors was approximately 40 and 60 times lower than that for 5-HT(1B/1D) receptors, respectively.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Almotriptan System Suitability, United States Pharmacopeia (USP) Reference Standard

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Almotriptan Related Compound A, United States Pharmacopeia (USP) Reference Standard

1013545

2-{5-[(Pyrrolidin-1-ylsulfonyl)methyl]-1H-indol-3-yl}ethanamine hemifumarate salt, United States Pharmacopeia (USP) Reference Standard

1013567

Almotriptan Related Compound D, United States Pharmacopeia (USP) Reference Standard

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Almotriptan Related Compound C, United States Pharmacopeia (USP) Reference Standard

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Almotriptan malate, CRS, European Pharmacopoeia (EP) Reference Standard

Y0002140

Almotriptan for system suitability, CRS, European Pharmacopoeia (EP) Reference Standard

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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