1604803
USP
Ritonavir
United States Pharmacopeia (USP) Reference Standard
Synonym(s):
1,3-Thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
About This Item
Recommended Products
biological source
synthetic
grade
pharmaceutical primary standard
agency
USP
vapor pressure
<0.0000001 kPa ( 25 °C)
API family
ritonavir
form
powder
packaging
pkg of 200 mg
manufacturer/tradename
USP
storage condition
protect from light
color
white to tan
solubility
acetonitrile: slightly soluble
ethanol: freely soluble
methanol: freely soluble
methylene chloride: freely soluble
water: practically insoluble
application(s)
pharmaceutical (small molecule)
format
neat
InChI
1S/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1
InChI key
NCDNCNXCDXHOMX-XGKFQTDJSA-N
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General description
Ritonavir belongs to the group of protease inhibitors that are widely used in combination with other drugs in the prevention of HIV. Its mode of action involves binding to the active site of the protease enzyme and preventing the further maturation of new viral particles.
Application
Also used to prepare standard, standard stock, identification, and standard working solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP):
- Lopinavir and Ritonavir Tablets
- Ritonavir Tablets
- Ritonavir
- Lopinavir and Ritonavir Oral Solution
Analysis Note
Other Notes
related product
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Related Content
This application note illustrates how it is possible to set-up an assay method for Lopinavir and Ritonavir tablets.
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