Skip to Content
MilliporeSigma
All Photos(2)

Documents

205354

Sigma-Aldrich

(Chloromethyl)trimethylsilane

98%

Synonym(s):

(Trimethylsilyl)methyl chloride

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
(CH3)3SiCH2Cl
CAS Number:
2344-80-1
Molecular Weight:
122.67
Beilstein/REAXYS Number:
906705
EC Number:
219-058-5
MDL number:
MFCD00000878
UNSPSC Code:
12352103
PubChem Substance ID:
24852326
NACRES:
NA.22

vapor pressure

~25 mmHg ( 20 °C)

Quality Level

100

assay

98%

form

liquid

refractive index

n20/D 1.418 (lit.)

bp

98-99 °C (lit.)

density

0.879 g/mL at 25 °C (lit.)

SMILES string

C[Si](C)(C)CCl

InChI

1S/C4H11ClSi/c1-6(2,3)4-5/h4H2,1-3H3

InChI key

OOCUOKHIVGWCTJ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

(Chloromethyl)trimethylsilane can be treated with aldehydes or ketones in the presence of triphenylphosphine to synthesize terminal alkenes. It can also be used in the preparation of a reagent, trimethylsilylmethyl magnesium chloride, commonly used in Peterson methylenation.

Packaging

The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 3

flash_point_f

24.8 °F - closed cup

flash_point_c

-4 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

Chloro(chloromethyl)dimethylsilane 98%

Sigma-Aldrich

226181

Chloro(chloromethyl)dimethylsilane

2-(Chloromethyl)allyl-trimethylsilane 97%

Sigma-Aldrich

318345

2-(Chloromethyl)allyl-trimethylsilane

Tris(trimethylsilyl)methane 97%

Sigma-Aldrich

302600

Tris(trimethylsilyl)methane

Direct synthesis of terminal olefins from ketones. Application of (chloromethyl) trimethylsilane to a Wittig reaction.
Sekiguchi A and Ando W
The Journal of Organic Chemistry, 44(3), 413-415 (1979)
Synthesis of alkenes from carbonyl compounds and carbanions alpha to silicon. III. Full report and a synthesis of the sex pheromone of gypsy moth.
Chan T H and Chang E
The Journal of Organic Chemistry, 39(22), 3264-3268 (1974)
Methylenation of Perfluoroalkyl Ketones using a Peterson Olefination Approach.
Hamlin T A, et al.
The Journal of Organic Chemistry, 79(3), 1145-1155 (2014)

Articles

Reagents for C–C Bond Formation

We carry a large variety of electrophiles and nucleophiles that are widely used in C–C bond-forming reactions. This group of products contains many organometallic reagents as well as commonly-used alkylating and acylating reagents.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service