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246557

Sigma-Aldrich

Tryptamine hydrochloride

99%

Synonym(s):

2-(3-Indolyl)ethylamine hydrochloride, 3-(2-Aminoethyl)indole hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C10H12N2 · HCl
CAS Number:
343-94-2
Molecular Weight:
196.68
Beilstein/REAXYS Number:
3568419
EC Number:
206-446-4
MDL number:
MFCD00012682
UNSPSC Code:
12352100
PubChem Substance ID:
24278134
NACRES:
NA.22

Quality Level

200

assay

99%

form

powder

mp

253-255 °C (lit.)

solubility

water: soluble 0.1 g/10 mL, clear to slightly hazy, colorless to yellow

SMILES string

Cl[H].NCCc1c[nH]c2ccccc12

InChI

1S/C10H12N2.ClH/c11-6-5-8-7-12-10-4-2-1-3-9(8)10;/h1-4,7,12H,5-6,11H2;1H

InChI key

KDFBGNBTTMPNIG-UHFFFAOYSA-N

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General description

The fluorescence property of tryptamine hydrochloride was studied in reverse micelles solution made with benzylhexadecyldimethylammonium chloride (BHDC) in benzene.

Application

Reactant for preparation of:
  • Tryptamine derivatives as inhibitors against hepatitis B virus
  • Carbamoyl epipodophyllotoxins as potential antitumor agents
  • Anthranilic acid derivatives as CCK receptor antagonists
  • Brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors
  • Antispasmodic agents
  • β-carbolinium cations as new antimalarial agents

Biochem/physiol Actions

Vasoactive; may have a neuromodulator function.

Other Notes

Biogenic amine formed from the decarboxylation of tryptophan by L-aromatic amino acid decarboxylase.

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1A

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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