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Supelco

1-Fluoro-2,4-dinitrobenzene

for HPLC derivatization, LiChropur™, ≥99.0% (GC)

Synonym(s):

2,4-Dinitro-1-fluorobenzene, DNFB, DNPF, FDNB, Sanger reagent

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About This Item

Linear Formula:
(O2N)2C6H3F
CAS Number:
70-34-8
Molecular Weight:
186.10
Beilstein/REAXYS Number:
398632
EC Number:
200-734-3
MDL number:
MFCD00007056
UNSPSC Code:
12000000
PubChem Substance ID:
329764683
NACRES:
NA.22

grade

for HPLC derivatization

Quality Level

100

assay

≥99.0% (GC)

form

(Solid or Semi-Solid or Chunk(s) or Paste or Liquid)

quality

LiChropur™

technique(s)

HPLC: suitable

color

light yellow to very dark green-yellow, and Light Green to Very Dark Green

refractive index

n20/D 1.569 (lit.)

bp

178 °C/25 mmHg (lit.)

mp

25-27 °C (lit.)

density

1.482 g/mL at 25 °C (lit.)

SMILES string

[O-][N+](=O)c1ccc(F)c(c1)[N+]([O-])=O

InChI

1S/C6H3FN2O4/c7-5-2-1-4(8(10)11)3-6(5)9(12)13/h1-3H

InChI key

LOTKRQAVGJMPNV-UHFFFAOYSA-N

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General description

1-Fluoro-2,4-dinitrobenzene is a color labeling agent, mainly used for detecting primary and secondary amines.

Application

1-Fluoro-2,4-dinitrobenzene may be used as a derivatizing reagent for the determination of gabapentin in human plasma samples, pharmaceutical formulations and memantine hydrochloride in pharmaceutical formulations using high-performance liquid chromatography technique.

Recommended products

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

flash_point_f

327.2 °F

flash_point_c

164 °C

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Certificates of Analysis (COA)

Lot/Batch Number
BCCD4534
BCCB2387
BCBZ3514
BCBW5362
BCBV1015

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A stability-indicating HPLC method for the determination of memantine hydrochloride in dosage forms through derivatization with 1-fluoro-2, 4-dinitrobenzene
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