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BP785

Anhydrous ampicillin

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Ampicillin, D-(−)-α-Aminobenzylpenicillin

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About This Item

Empirical Formula (Hill Notation):
C16H19N3O4S
CAS Number:
69-53-4
Molecular Weight:
349.40
Beilstein/REAXYS Number:
1090925
EC Number:
200-709-7
MDL number:
MFCD00005175
UNSPSC Code:
12352200
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

ampicillin

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

mp

208 °C (dec.) (lit.)

application(s)

pharmaceutical

format

neat

storage temp.

2-8°C

SMILES string

[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3)C(O)=O

InChI

1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1

InChI key

AVKUERGKIZMTKX-NJBDSQKTSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Anhydrous ampicillin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Co-fluampicil Oral Suspension
  • Co-fluampicil Capsules
  • Ampicillin Oral Suspension
  • Ampicillin Injection
  • Ampicillin Capsules
  • Ampicillin Trihydrate and Cloxacillin Benzathine Intramammary Infusion (Dry Cow)
  • Piperacillin Infusion
  • Ampicillin Sodium and Cloxacillin Sodium Intramammary Infusion (Lactating Cow)

    • Biochem/physiol Actions

    Mode of Action: Ampicillin is a semisynthetic penicillin and a ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane.

    Mode of Resistance: Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it.

    Antimicrobial Spectrum: Effective against both Gram-positive (similar to benzylpenicillin) and Gram-negative bacteria (similar to tetracyclines and chloramphenicol.

    Packaging

    Unit quantity: 250 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    pictograms

    Health hazard
    GHS08

    signalword

    Danger

    Hazard Classifications

    Resp. Sens. 1 - Skin Sens. 1

    Storage Class

    11 - Combustible Solids

    wgk_germany

    WGK 2

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

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