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V5639

Sigma-Aldrich

Anti-Versican V0/V1 Neo antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL number:
MFCD07370544
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human, rat

technique(s)

western blot: 1 μg/mL using mouse cumulus oocyte complexes

UniProt accession no.

P13611

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... VCAN(1462)
mouse ... Vcan(13003)
rat ... Vcan(114122)

Immunogen

synthetic peptide corresponding to amino acid residues 436-441 from human versican protein. This sequence is completely conserved between human, mouse and rat.

Physical form

Solution in phosphate buffered saline containing 1.0 mg/ml BSA and 0.05% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Ewa M Koźma et al.
Glycobiology, 21(10), 1301-1316 (2011-05-06)
Organ fibrosis is associated with excessive deposition of dermatan sulfate (DS) in the extracellular matrix (ECM) of the affected tissue. However, the significance of DS in fibrosis process is poorly known. Thus, we have analyzed both in vitro and in
Thomas N Wight
Current opinion in cell biology, 14(5), 617-623 (2002-09-17)
Versican is a large extracellular matrix proteoglycan that is present in a variety of tissues. Successful cloning of the gene in man, mouse, cow and chicken has revealed the existence of at least four splice variants of versican, which differ
Wang Sheng et al.
Molecular biology of the cell, 16(3), 1330-1340 (2005-01-07)
Versican is a large chondroitin sulfate proteoglycan belonging to the lectican family. Alternative splicing of versican generates at least four isoforms named V0, V1, V2, and V3. We have shown that the versican V1 isoform not only enhanced cell proliferation
Sabrina Cattaruzza et al.
The Journal of biological chemistry, 277(49), 47626-47635 (2002-09-11)
We have carried out a comprehensive molecular mapping of PG-M/versican isoforms V0-V3 in adult human tissues and have specifically investigated how the expression of these isoforms is regulated in endothelial cells in vitro. A survey of 21 representative tissues highlighted
Dingcheng Gao et al.
Cancer research, 72(6), 1384-1394 (2012-01-28)
Tumors systemically initiate metastatic niches in distant target metastatic organs. These niches, composed of bone marrow-derived hematopoietic cells, provide permissive conditions for future metastases. However, the mechanisms by which these cells mediate outgrowth of metastatic tumor cells are not completely

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