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Sigma-Aldrich

2,3-Dimercapto-1-propanol tributyrate

97%

Synonym(s):

BAL tributyrate

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About This Item

Linear Formula:
CH3CH2CH2CO2CH2CH(SCOCH2CH2CH3)CH2SCOCH2CH2CH3
CAS Number:
58428-97-0
Molecular Weight:
334.49
MDL number:
MFCD00010601
UNSPSC Code:
12352100
PubChem Substance ID:
24857046
NACRES:
NA.22

Quality Level

100

assay

97%

form

liquid

refractive index

n20/D 1.495 (lit.)

bp

156-160 °C/0.15 mmHg (lit.)

density

1.083 g/mL at 25 °C (lit.)

SMILES string

CCCC(=O)OCC(CSC(=O)CCC)SC(=O)CCC

InChI

1S/C15H26O4S2/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3

InChI key

NHBKXEKEPDILRR-UHFFFAOYSA-N

Related Categories

Application

2,3-Dimercapto-1-propanol tributyrate is a thioester analog of triacylglycerol and has been used:
  • in lipase inhibition assay during in vitro screening of medicinal plants as antidiabetics with glucosidase and lipase inhibitory activities
  • in colorimetric microplate assay for lipase activity
  • to analyze positional specificity of LipG (lipase-encoding gene) toward triacylglycerol by a simple continuous spectrophotometric method

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

wgk_germany

WGK 3

flash_point_f

closed cup

flash_point_c

closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Certificates of Analysis (COA)

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Mi-Hwa Lee et al.
Applied and environmental microbiology, 72(11), 7406-7409 (2006-09-05)
We cloned lipG, which encoded a lipolytic enzyme, from a Korean tidal flat metagenomic library. LipG was related to six putative lipases previously identified only in bacterial genome sequences. These enzymes comprise a new family. We partially characterized LipG, providing
Suk-Jung Choi et al.
Journal of biochemistry and molecular biology, 36(4), 417-420 (2003-08-05)
The present work describes a colorimetric microplate assay for lipase activity based on the reaction between 5,5'-dithiobis(2-nitro benzoic acid) (DTNB) and the hydrolysis product of 2,3-dimercapto-1-propanol tributyrate (DMPTB). Reaction mixtures containing DTNB, DMPTB, and lipase were prepared in microplate wells
[A new simplified colorimetric assay of colipase in duodenal juice using BALB as substrate and its clinical application].
Y Furukawa et al.
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 83(7), 1367-1375 (1986-07-01)
S Lombard et al.
The Biochemical journal, 358(Pt 3), 773-781 (2001-09-06)
The present study was carried out with a view of determining ricin lipolytic activity on neutral lipids in emulsion and in a membrane-like model. Using 2,3-dimercapto-1-propanol tributyrate (BAL-TC(4)) as substrate, the lipolytic activity of ricin was found to be proportional
Guillermo Ramírez et al.
Evidence-based complementary and alternative medicine : eCAM, 2012, 701261-701261 (2012-10-20)
This work shows the inhibitory effect on glucosidase and lipase enzymes of 23 medicinal plants described as traditional treatments for diabetes in several Mexican sources. Hydroalcoholic extracts of selected plants were evaluated at 1 mg/mL for glucosidase and 0.25 mg/mL for lipase
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